Faculty of Public Health - Andalas University - OCS, 13th IEA SEA Meeting and ICPH - SDev

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Early diagnosis and management of persistent pulmonary hypertension of the newborn in Pelni Hospital Jakarta
Suprohaita Rusdi Talib

Last modified: 2018-09-16

Abstract


Background

Persistent pulmonary hypertension of the newborn (PPHN) is defined as the failure of the normal circulation transition that occurs after birth. It characterized by marked pulmonary hypertension that causes hypoxemia secondary to right-to-left shunting of blood at the foramen ovale and ductus arteriosus. Signs and symptoms of perinatal distress such as asphyxia, tachypnea, respiratory distress, cyanosis, and systemic hypotension in early life must be considered PPHN as diagnosis. Echocardiography is the most reliable noninvasive test to establish the diagnosis, assess cardiac function, and exclude associated structural heart disease.

Materials and methods

A case series of PPHN patient in Perinatology/Neonatal Intensive Care Unit Pelni Hospital Jakarta from Januari to July 2018.

 

Results

All patient with respiratory distress and cyanosis were performed oxygen saturation and echocardiography. Early neonatal (0-7 days) was crucial period for early management. All patient had severe tricuspid regurgitation and right-to-left shunting of blood at the foramen ovale and/or ductus arteriosus. After oxygenation dan administration of combination vasodilator drugs and diuretic, most of patient had significant clinically improvement.

 

Conclusions

Early diagnosis and management of PPHN improve the outcome. Echocardiography is important tool for diagnosis of PPHN. After exclude critical congenital heart disease with duct dependent lesion, oxygenation dan administration of combination vasodilator drugs and diuretic can improve outcome.

 

Acknowledgements

Perinatology/Neonatal Intensive Care Unit and Cardiovascular Technician Team of Pelni Hospital Jakarta

 

Keywords : pulmonary hypertension, diagnosis, management