Faculty of Public Health - Andalas University - OCS, 13th IEA SEA Meeting and ICPH - SDev

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Serprevalence Of Varicella Zoaster Virus For India: A Systematic Review And Meta Analysis
Seema Patrikar, Shruti Vashisht

Last modified: 2018-08-10

Abstract


Background

Primary Varicella-zoster virus (VZV) infection results in chickenpox (varicella), having a 2-week incubation period and highly contagious with attack rate ranging from 61-100% among susceptible individuals. The risks of varicella infection increase after 15 years of age and are particularly great in those aged 20 years and older. Identification of VZV seroprevalance rate in general population may lead to develop new health strategic managements such as vaccination. Therefore, this systematic  review of the seroprevalence of VZV infection among Indian population was carried out.

Materials and methods

A systematic and comprehensive literature search was carried out in electronic databases such as PubMed, Web of knowledge, Scopus, Science Direct, Google Scholar for India. Data was analyzed using random effect model and heterogeneity tested using I-square statistics.

Results

Of the total fourteen studies, five studies post 2000 with total sample size of 2876 individuals were included in the review. The overall seroprevalence rate of VZV infection in general population of India was 72.48% (95% CI; 68.21%-76.56%). There was significant heterogeneity among the studies (p=0.003, I2=98%).

Conclusions

The review represents the seroprevalence of VZV infection in India and generates evidence for immunization program.

Keywords: Varicella,  seroprevalence,  India