Faculty of Public Health - Andalas University - OCS, 13th IEA SEA Meeting and ICPH - SDev

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Mung Bean Sprout for Oxidative Stress Prevention
Muhammad Asrullah

Last modified: 2018-09-16

Abstract


Background

High fat consumption that caused dyslipidemia is a risk factor of cardiovascular disease. It also produced aldehyde compound that naturally toxic and can damage membrane plasma and heart tissue. The consumption of rich antioxidant diet including vitamin E like mung bean sprout can prevent the cardiovascular disease. The aim of this study is to evaluate the effect of mung bean sprout consumption to oxidative stress by triglycerides, High Density Lipoprotein (HDL), and liver Malondialdehyde (MDA) parameter in rats.

Materials and methods

Four groups of six male Sprague Dawley rats (aged 2 months) were included in this study.  Group I got the standard diet, group II got a high-fat diet, group III was treated with mung bean sprouts 1 mL/200 g body weight along with high fat diet, and group IV was treated vitamin E doses of 23 IU/ 200 g body weight along with high fat diet. After 28 days of intervention, several parameters were measured using the GPO-PAP for serum triglyceride, CHOD-PAP for serum HDL, and method from Singh et al. (2002) for liver MDA

Results

Triglycerides and liver MDA were lower and HDL levels were higher in group III rats than the group II rats. There is no significant different between the rats group III and group IV. The serum triglycerides have positive correlation and HDL have negative correlation to MDA liver

Conclusion

Mung bean sprout prevent the increasing of serum triglyceride and MDA liver concentration and decreasing of serum HDL in rat along with high fat diet

Keywords: Triglycerides, HDL, MDA liver, mung bean sprouts